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Updated: Aug 16, 2026

Methods to Assess Beta Cell Death Mediated by Cytotoxic T Lymphocytes
12:12

Methods to Assess Beta Cell Death Mediated by Cytotoxic T Lymphocytes

Published on: June 16, 2011

APO-1/(Fas/CD95) によって媒介されたオトクリンT細胞自殺

J Dhein1, H Walczak, C Bäumler

  • 1Tumorimmunology Program, German Cancer Research Center, Heidelberg.

Nature
|February 2, 1995
PubMed
まとめ

T細胞受容体活性化は,ヒトT細胞におけるAPO-1 (Fas/CD95とも呼ばれる) 媒介によるアポトーシスを誘発する. APO-1リガンドを含むこの経路は,T細胞の消去と免疫応答の調節を説明する.

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