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Updated: May 12, 2026

Isolation and Th17 Differentiation of Naïve CD4 T Lymphocytes
12:59

Isolation and Th17 Differentiation of Naïve CD4 T Lymphocytes

Published on: September 27, 2013

B7-1とB7-2の共刺激性分子は,Th1/Th2の発達経路を差異的に活性化します:自己免疫疾患の治療への応用

V K Kuchroo1, M P Das, J A Brown

  • 1Department of Neurology, Harvard Medical School, Boston, Massachusetts 02115.

Cell
|March 10, 1995
PubMed
まとめ

コスティミュレータ分子B7-1とB7-2は,Tヘルパー細胞の分化をT1とT2経路に微分的に調節する. これらの分子を操作すると,シトカインプロファイルを変えることで,実験的なアレルギー性脳内炎 (EAE) 疾患の発生率と重症度に影響を与えます.

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