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Updated: May 8, 2026

Identification of Kinase-substrate Pairs Using High Throughput Screening
11:13

Identification of Kinase-substrate Pairs Using High Throughput Screening

Published on: August 29, 2015

p19Skp1とp45Skp2は,サイクリンA-CDK2S相キナーゼの必須要素である

H Zhang1, R Kobayashi, K Galaktionov

  • 1Howard Hughes Medical Institute, Cold Spring Harbor Laboratory, New York 11724, USA.

Cell
|September 22, 1995
PubMed
まとめ

研究者らは,p45が細胞サイクルS相への入り口に不可欠なサイクリンA-CDK2キナーゼ活性に不可欠であることを特定しました. 変形細胞におけるp45の増加は,細胞サイクル制御を変化させることで,細胞変容を誘導する可能性があります.

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Identification of Cyclin-dependent Kinase 1 Specific Phosphorylation Sites by an In Vitro Kinase Assay12:26

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