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Updated: Aug 13, 2026

Studying TGF-β Signaling and TGF-β-induced Epithelial-to-mesenchymal Transition in Breast Cancer and Normal Cells
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WDドメインのタンパク質で,II型TGF-β受容体と関連し,その受容体によってリン酸化される

R H Chen1, P J Miettinen, E M Maruoka

  • 1Department of Growth and Development, University of California at San Francisco 94143-0640, USA.

Nature
|October 12, 1995
PubMed
まとめ

研究者らは,成長因子-β (TGF-β) 型受容体と結合するタンパク質であるTRIP-1を発見した. この相互作用は,TGF-βシグナル伝達に不可欠であり,真核生物の間で保存され,基本的な生物学的役割を果たしていることを示唆しています.

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