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Updated: Jul 29, 2026

Identification of Intracellular Signaling Events Induced in Viable Cells by Interaction with Neighboring Cells Undergoing Apoptotic Cell Death
09:18

Identification of Intracellular Signaling Events Induced in Viable Cells by Interaction with Neighboring Cells Undergoing Apoptotic Cell Death

Published on: December 27, 2016

哺乳類のアポトーシスに必要なICE/CED-3プロテアゼの特定と抑制

D W Nicholson1, A Ali, N A Thornberry

  • 1Department of Biochemistry and Molecular Biology, Merck Frosst Centre for Therapeutic Research, Pointe Claire-Dorval, Quebec, Canada.

Nature
|July 6, 1995
PubMed
まとめ

研究者らは,アポパイン (CPP32とも呼ばれる) を精製し,アポトーシス (プログラム細胞死) に不可欠なプロテアスを生成した. 抑制剤は細胞死を防止し,apopain/CPP32を確認した.

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