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Updated: Sep 1, 2026

Spatio-Temporal Manipulation of Small GTPase Activity at Subcellular Level and on Timescale of Seconds in Living Cells
10:27

Spatio-Temporal Manipulation of Small GTPase Activity at Subcellular Level and on Timescale of Seconds in Living Cells

Published on: March 9, 2012

小さなGTP結合タンパク質であるRac1とCdc42は,JNK/SAPKシグナル伝達経路の活動を調節する

O A Coso1, M Chiariello, J C Yu

  • 1Molecular Signaling Unit, National Institute of Dental Research, National Institutes of Health, Bethesda, Maryland 20892, USA.

Cell
|June 30, 1995
PubMed
まとめ

Rac1とCdc42のGTPアゼは,c-Junアミノ端末キナーゼ (JNK) 信号伝達の主要な調節体である. これらのRho関連タンパク質は,Rasとは異なり,JNKを活性化し,JNKがサイトカインや成長因子に対する反応に不可欠です.

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Comparing the Affinity of GTPase-binding Proteins using Competition Assays10:37

Comparing the Affinity of GTPase-binding Proteins using Competition Assays

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Detection of Small GTPase Prenylation and GTP Binding Using Membrane Fractionation and GTPase-linked Immunosorbent Assay13:51

Detection of Small GTPase Prenylation and GTP Binding Using Membrane Fractionation and GTPase-linked Immunosorbent Assay

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