関連する実験動画

Updated: Feb 16, 2026

Preparation of Nucleosome Core Particles Complexed with DNA Repair Factors for Cryo-Electron Microscopy Structural Determination
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Preparation of Nucleosome Core Particles Complexed with DNA Repair Factors for Cryo-Electron Microscopy Structural Determination

Published on: August 17, 2022

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フォトリアーゼの構造:DNA修復のために光子エネルギーを利用する

J E Hearst1

  • 1Department of Chemistry, University of California, Berkeley 94720-1460, USA.

Science (New York, N.Y.)
|June 30, 1995
PubMed
まとめ

No abstract available in PubMed .

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One of the common DNA damages is the chemical alteration of single bases by alkylation, oxidation, or deamination. The altered bases cause mispairing and strand breakage during replication. This type of damage causes minimal change to the DNA double helix structure and can be repaired by the base excision repair (BER) pathways. BER corrects damaged DNA sequences by removing the damaged base and restoring the original base sequence using the complementary strand as a template.
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