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Updated: Aug 13, 2026

Detection and Visualization of DNA Damage-induced Protein Complexes in Suspension Cell Cultures Using the Proximity Ligation Assay
13:10

Detection and Visualization of DNA Damage-induced Protein Complexes in Suspension Cell Cultures Using the Proximity Ligation Assay

Published on: June 9, 2017

ミトゲン活性化Tリンパ球におけるDNA損傷誘発のアポプトシスのIRF-1-依存経路

T Tamura1, M Ishihara, M S Lamphier

  • 1Department of Immunology, Faculty of Medicine, University of Tokyo, Japan.

Nature
|August 17, 1995
PubMed
まとめ

DNA損傷は,インターフェロン調節因子 (IRF) -1を含む経路を通じてTリンパ球のアポトーシスを引き起こす. このIRF-1に依存する経路は,チモサイトで見られるp53経路とは異なり,ユニークな細胞防衛機構を強調しています.

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