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Updated: Aug 11, 2026

Affinity Precipitation of Active Rho-GEFs Using a GST-tagged Mutant Rho Protein (GST-RhoA(G17A)) from Epithelial Cell Lysates
11:28

Affinity Precipitation of Active Rho-GEFs Using a GST-tagged Mutant Rho Protein (GST-RhoA(G17A)) from Epithelial Cell Lysates

Published on: March 31, 2012

グアニン-ヌクレオチド交換因子ヒトMss4の構造と,そのRab相互作用表面の識別

H Yu1, S L Schreiber

  • 1Howard Hughes Medical Institute, Department of Chemistry, Harvard University, Cambridge, Massachusetts 02138, USA.

Nature
|August 31, 1995
PubMed
まとめ

人間のMss4 (hMss4) は,グアニン・ヌクレオチド交換因子 (GEF) であり,決定的な三次構造を有する. この構造は,その活性部位がZn2+結合領域と,Rabタンパク質の調節に不可欠な隣接するループを含むことを明らかにします.

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