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Updated: Aug 4, 2026

Dissection of the Transversus Abdominis Muscle for Whole-mount Neuromuscular Junction Analysis
06:12

Dissection of the Transversus Abdominis Muscle for Whole-mount Neuromuscular Junction Analysis

Published on: January 11, 2014

ラプシン欠乏マウスの神経筋肉の接合点において,ポストシナプス的な専門化が発達しない

M Gautam1, P G Noakes, J Mudd

  • 1Department of Molecular Biology, Washington University Medical School, St. Louis, Missouri 63110, USA.

Nature
|September 21, 1995
PubMed
まとめ

ラプシン (Rapsyn) は,神経筋の接合点におけるニコチン性アセチルコリン受容体 (AChR) のクラスター形成に不可欠である. しかし,AChR遺伝子のシナプス特異的転写は,ラプシンがない場合でも発生します.

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Characterization of Neuromuscular Junctions in Mice by Combined Confocal and Super-Resolution Microscopy11:03

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Postsynaptic Potential (PSP)01:32

Postsynaptic Potential (PSP)

Postsynaptic potential (PSP) refers to a change in the electrical potential of a neuron when neurotransmitters released by presynaptic neurons bind to postsynaptic receptors. This potential can either be excitatory, leading to depolarization and ultimately action potential generation, or inhibitory, leading to hyperpolarization and suppression of the postsynaptic neuron.
There are two types of receptors: ionotropic and metabotropic.
The ionotropic receptor is the membrane protein that has an...