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Updated: May 2, 2026

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MHCクラスIIに関連するインヴァリアントチェーンが欠けているマウスは,

S Viville1, J Neefjes, V Lotteau

  • 1Laboratorie de Génétique Moléculaire des Eucaryotes du CNRS, Strasbourg, France.

Cell
|February 26, 1993
PubMed
まとめ

インヴァリアントチェーン (li) を欠いたマウスは,MHCIIクラス分子輸送の障害を示している. この欠陥は抗原のプレゼンテーションを低下させ,CD4+T細胞の発達に影響を与え,免疫機能における重要な役割を強調する.

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