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Updated: Aug 17, 2026

Peptide-based Identification of Functional Motifs and their Binding Partners
14:28

Peptide-based Identification of Functional Motifs and their Binding Partners

Published on: June 30, 2013

膜腫瘍ネクロシス因子-αは,HIVに感染したヒトT細胞によって誘発されるポリクローンB細胞の活性化に関与しています

D Macchia1, F Almerigogna, P Parronchi

  • 1Division of Clinical Immunology and Allergology, University of Florence, Italy.

Nature
|June 3, 1993
PubMed
まとめ

ヒト免疫不全ウイルス-1 (HIV-1) がCD4+T細胞に感染すると,逆説的にB細胞が活性化します. 感染したT細胞の膜腫瘍死滅因子アルファ (TNF-α) は,このB細胞の活性化と免疫グロブリン生成を誘発する.

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