関連する実験動画

Updated: Sep 7, 2026

Retroviral Transduction of T-cell Receptors in Mouse T-cells
10:14

Retroviral Transduction of T-cell Receptors in Mouse T-cells

Published on: October 22, 2010

T細胞抗原受容体複合体のゼータ鎖が欠けているマウスのT細胞細胞発達

P E Love1, E W Shores, M D Johnson

  • 1Laboratory of Mammalian Genes and Development, National Institute of Child Health and Human Development, National Institutes of Health (NIH), Bethesda, MD 20892.

Science (New York, N.Y.)
|August 13, 1993
PubMed
まとめ

ゼータサブユニットは,T細胞発育に不可欠であり,チモサイトの分化とT細胞受容体発現に影響を与えます. ゼータ発現を欠いたマウスは,T細胞の生成が低下したが,欠落していないことを示した.

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T Cell Activation and Clonal Selection01:22

T Cell Activation and Clonal Selection

T cells are integral to our adaptive immune system, recognizing and effectively responding to foreign antigens. T cell activation and clonal selection are pivotal in orchestrating this immune response. This article elucidates these mechanisms, detailing the roles of cluster of differentiation (CD) markers, major histocompatibility complex (MHC) molecules, costimulatory signals, and the process of clonal selection.
Naive T cells that have not yet encountered an antigen express two primary CD...