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Updated: Jul 5, 2026

Generation of Human CD40-activated B cells
13:27

Generation of Human CD40-activated B cells

Published on: October 17, 2009

抗原受容体のクロスリンクによって誘発されるB細胞アポトシスは,CD40を通じたT細胞信号によってブロックされます

T Tsubata1, J Wu, T Honjo

  • 1Department of Medical Chemistry, Kyoto University Faculty of Medicine, Japan.

Nature
|August 12, 1993
PubMed
まとめ

自己反応性B細胞は,表面免疫グロブリン (sIg) マルチメリゼーションによって除去されます. T細胞の助け,特にCD40シグナリングは,このB細胞アポトシスを防止し,排除の代わりに活性化を促します.

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Murine Model of CD40-activation of B cells12:24

Murine Model of CD40-activation of B cells

Published on: March 6, 2010

Identification of Mediators of T-cell Receptor Signaling via the Screening of Chemical Inhibitor Libraries08:49

Identification of Mediators of T-cell Receptor Signaling via the Screening of Chemical Inhibitor Libraries

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