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Updated: Aug 11, 2026

Investigating Mast Cell Secretory Granules; from Biosynthesis to Exocytosis
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B細胞におけるヒトIgE合成の誘導は,マスト細胞とベースフィールによって行われる

J F Gauchat1, S Henchoz, G Mazzei

  • 1Glaxo Institute for Molecular Biology, Geneva, Switzerland.

Nature
|September 23, 1993
PubMed
まとめ

アレルギーにおける重要な役割を果たすマスト細胞とベースフィルは,免疫グロブリンE (IgE) の産生を直接調節することができます. これらの細胞は,IgE合成を刺激するCD40リンガンド (CD40L) を発現し,炎症媒介体を放出する以上の新しい役割を示唆しています.

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