関連する実験動画

Updated: Aug 13, 2026

Generating De Novo Antigen-specific Human T Cell Receptors by Retroviral Transduction of Centric Hemichain
08:48

Generating De Novo Antigen-specific Human T Cell Receptors by Retroviral Transduction of Centric Hemichain

Published on: October 25, 2016

リンパ性細胞のT細胞とB細胞の抗原受容体を通じたシグナル伝達に欠陥があり,その細胞にVAV原発がん遺伝子が欠けている

R Zhang1, F W Alt, L Davidson

  • 1Division of Hematology/Oncology, Children's Hospital, Boston, Massachusetts 02115, USA.

Nature
|March 30, 1995
PubMed
まとめ

vav原発がん遺伝子は,T細胞とB細胞の発達と活性化に不可欠です. 欠乏すると免疫不全が生じ,免疫細胞の信号伝達と機能におけるその役割を強調する.

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