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Updated: Aug 8, 2026

Use of Single Chain MHC Technology to Investigate Co-agonism in Human CD8+ T Cell Activation
12:09

Use of Single Chain MHC Technology to Investigate Co-agonism in Human CD8+ T Cell Activation

Published on: February 28, 2019

超抗原依存性,細胞媒介性サイト毒性は,Tリンパ球のMHCクラスI受容体によって抑制される

J H Phillips1, J E Gumperz, P Parham

  • 1Department of Human Immunology, DNAX Research Institute of Molecular and Cellular Biology, Palo Alto, CA 94304, USA.

Science (New York, N.Y.)
|April 21, 1995
PubMed
まとめ

細菌の超抗原はT細胞の活性化を誘発し,病気を引き起こす. NKB1のようなT細胞の阻害受容体は,ヒト白血球抗原 (HLA) クラスI分子を標的とし,組織損傷を潜在的に制限することによって,この活性化をブロックすることができます.

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