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Updated: May 7, 2026

Characterize Disease-related Mutants of RAF Family Kinases by Using a Set of Practical and Feasible Methods
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Characterize Disease-related Mutants of RAF Family Kinases by Using a Set of Practical and Feasible Methods

Published on: July 17, 2019

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体受容体チロシンキナーゼは,Ras-独立経路でRafを活性化することができます

X S Hou1, T B Chou, M B Melnick

  • 1Department of Genetics, Harvard Medical School, Boston, Massachusetts 02115, USA.

Cell
|April 7, 1995
PubMed
まとめ

体受容体チロシンキナーゼ (RTK) は,Ras1シグナル伝達とは独立してD-Rafキナーゼを活性化することができます. この研究は,RTK媒介のD-Raf活性化のための新しいRas独立経路を in vivoで明らかにしています.

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