高齢者医療とは

T M Gill¹, M E Tinetti

¹Yale University School of Medicine, New Haven, Conn, USA.

JAMA

|June 7, 1995

まとめ

この研究は,高齢者のコレステロールと冠動脈性心疾患 (CHD) の関連性に異議を唱えている. しかし,高血圧の薬物治療は,脳卒中と心血管疾患のリスクを大幅に低下させます.

科学分野:

ゲロントロジーはゲロントロジーの学科です.
心血管医学心血管医学
公衆衛生は公衆衛生である.

背景:

血中コレステロールと冠動脈疾患 (CHD) の発生率の関係は,依然として重要な研究分野です.
高血圧管理は,心血管および脳血管イベントの軽減に不可欠です.

研究の目的:

血液中のコレステロール値と,70歳以上の個体において,心血管疾患の発生率または心血管疾患による死亡率との関連を調査する.
軽度から中等度の高血圧に対する薬物治療が,脳卒中および心血管疾患による罹病率および死亡率に与える影響を評価する.

主な方法:

70歳以上の参加者を含む将来的な研究設計.
血中コレステロール値,心臓病発生率,死亡率に関するデータの分析.
高血圧の薬物治療を受けている患者のアウトカムの評価.

主要な成果:

血液中のコレステロール値と心血管疾患の発生率,または高齢者の関連死亡率との直接的な関連を否定する証拠が見つかりました.
軽度から中等度の高血圧に対する薬物治療は,脳卒中と心血管疾患の罹患率と死亡率の両方を大幅に減少させることが示されました.

結論:

この研究結果は,コレステロールの血中濃度が70歳以上の人の心臓病の主要な危険因子ではないことを示唆しています.
薬物療法による高血圧の効果的な管理は,脳卒中や心血管疾患を含む主要な心血管および脳血管疾患の予防に不可欠です.

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