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Updated: Aug 15, 2026

OaAEP1-Mediated Enzymatic Synthesis and Immobilization of Polymerized Protein for Single-Molecule Force Spectroscopy
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OaAEP1-Mediated Enzymatic Synthesis and Immobilization of Polymerized Protein for Single-Molecule Force Spectroscopy

Published on: February 5, 2020

モジュール型ポリケチド合成酵素におけるドメインの位置変更により,特定の鎖分裂を促進します

J Cortes1, K E Wiesmann, G A Roberts

  • 1Cambridge Centre for Molecular Recognition, University of Cambridge, UK.

Science (New York, N.Y.)
|June 9, 1995
PubMed
まとめ

研究者は,ポリケチド合成を制御するために,6-デオキシエリトロノリドB合成酵素 (DEBS) を改変した. サイクラスドメインの位置変更により,特定のポリケチド構造の形成が加速され,薬物開発のための新しい方法が提供されました.

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