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Updated: Jul 28, 2026

Detection of Toxin Translocation into the Host Cytosol by Surface Plasmon Resonance
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Published on: January 3, 2012

クロストリジウムディフィシル毒素BによるRhoタンパク質のグルコシル化

I Just1, J Selzer, M Wilm

  • 1Institut für Pharmakologie und Toxikologie, Universität des Saarlandes, Homburg/Saar, Germany.

Nature
|June 8, 1995
PubMed
まとめ

クロストリジウムディフィシル毒素Bは,グルコースを加えることでRhoAGTPアゼを改変し,それを無効化する. このグルコシル化RhoAはアクチン細胞骨格を破壊し,細胞損傷を引き起こし,大腸炎に寄与します.

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