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Updated: Aug 9, 2026

Identification of Kinase-substrate Pairs Using High Throughput Screening
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Published on: August 29, 2015

タンパク質-チロシンキナーゼの触媒的特異性は,選択的シグナル伝達に極めて重要です

Z Songyang1, K L Carraway, M J Eck

  • 1Department of Medicine, Beth Israel Hospital, Boston, Massachusetts 02215.

Nature
|February 9, 1995
PubMed
まとめ

タンパク質チロシンキナーゼ (PTKs) は,その触媒部位とSH2ドメインによって影響されるユニークな基板特異性を示しています. この特異性は,細胞信号伝達に不可欠であり,変異によって変化し,ヒトの病気に影響を与える可能性があります.

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