結核のコントロールの指標として,コミュニティ感染率
G Madico1, R H Gilman, W Checkley
1AB Prisma, Lima, Peru.
Lancet (London, England)
|February 18, 1995
まとめ
ペルーのスラム街での結核の伝播は,家庭内だけでなく,コミュニティーベースのものであることが多い. この発見は,現在の結核対策戦略が,感染頻度が高い地域社会に適応する必要があることを示唆している.
科学分野:
- エピデミオロジー エピデミオロジー
- 感染症 感染症は感染症です.
- 公衆衛生は公衆衛生である.
背景:
- 結核 (TB) の疫学については,特に脆弱な集団における伝播動態について,さらなる理解が必要である.
- 家庭とコミュニティの拡散のバランスを調査することは,効果的な結核対策に不可欠です.
研究 の 目的:
- 子どもにおけるMycobacterium tuberculosisの家庭内感染とコミュニティでの感染の相対的な重要性を決定する.
- ペルーのスランタウンの環境で結核感染の危険因子を評価するために.
主な方法:
- 結核に感染した家庭の175人の子供 (接触者) と,感染していない家庭の382人の子供 (対照者) を対象とした横断的な研究.
- Mycobacterium tuberculosisへの曝露の流行は,浄化タンパク質誘導体 (PPD) 皮膚検査を使用して測定されました.
- 感染源を区別するために,コミュニティ感染比率 (CIR) を計算した.
主要な成果:
- 接触児の55%と対照児の34%がPPD陽性であった.
- 接触家庭での生活と年齢の上昇は,PPD陽性性の重要なリスク要因でした.
- 調整されたオッズ比率は,他の研究と比較して,この設定でコミュニティでの感染の可能性が高いことを示しました.
結論:
- この研究は,調査されたペルーのスランタウンのコミュニティでの結核の有意な伝播を強調しています.
- 主に家庭での接触に焦点を当てた現在の結核対策戦略は,コミュニティでの感染率が高い地域では不十分かもしれない.
- 家庭外での結核の蔓延に対処するために,適応された公衆衛生の介入が必要である.
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