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Updated: May 12, 2026

Studying Age-dependent Genomic Instability using the S. cerevisiae Chronological Lifespan Model
08:46

Studying Age-dependent Genomic Instability using the S. cerevisiae Chronological Lifespan Model

Published on: September 29, 2011

静止遺伝子のSIR4の変異は,S. cerevisiaeの老化を遅らせる可能性があります

B K Kennedy1, N R Austriaco, J Zhang

  • 1Department of Biology, Massachusetts Institute of Technology, Cambridge 02139.

Cell
|February 10, 1995
PubMed
まとめ

研究者らは,酵母細胞の寿命を30%以上大幅に延長するSIR4遺伝子の変異を特定しました. これは,特定の染色体領域における遺伝子サイレンシングを維持することが,細胞の老化を防ぐために重要であることを示唆しています.

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A Suppressor Screen for the Characterization of Genetic Links Regulating Chronological Lifespan in Saccharomyces cerevisiae10:39

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