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Updated: Aug 10, 2026

Using Confocal Analysis of Xenopus laevis to Investigate Modulators of Wnt and Shh Morphogen Gradients
08:10

Using Confocal Analysis of Xenopus laevis to Investigate Modulators of Wnt and Shh Morphogen Gradients

Published on: December 14, 2015

ローカルおよび長距離シグナリングで活躍するヘッジホッグの自己プロテオリスティック・クリバージュの産物

J A Porter1, D P von Kessler, S C Ekker

  • 1Howard Hughes Medical Institute, Department of Molecular Biology and Genetics, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205.

Nature
|March 23, 1995
PubMed
まとめ

ヘッジホッグ (hh) タンパク質は,自己タンパク質分解を経て,発達パターンをシグナルする. 研究者らは,分裂部位を特定し,アミノ端末 (N) 断片が活性信号分子であることを明らかにした.

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