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Updated: Aug 18, 2026

In Vitro Directed Evolution of a Restriction Endonuclease with More Stringent Specificity
09:16

In Vitro Directed Evolution of a Restriction Endonuclease with More Stringent Specificity

Published on: March 25, 2020

Nae I制限エンドヌクレアゼにおけるDNAトポイソメラーゼと再結合酵素の活動

K Jo1, M D Topal

  • 1Lineberger Comprehensive Cancer Center, Department of Biochemistry and Biophysics, University of North Carolina Medical School, Chapel Hill 27599.

Science (New York, N.Y.)
|March 24, 1995
PubMed
まとめ

Nae Iエンドヌクレアース酵素は,DNAリガース活性を調べるために改変されました. この改変により,結合されたエンドヌクレアゼとリガゼの機能が明らかになり,Nae Iをトポイソメラーゼと再結合酵素ファミリーと結びつけました.

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