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Updated: Apr 29, 2026

Systems Biology of Metabolic Regulation by Estrogen Receptor Signaling in Breast Cancer
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c-ErbAによるリガンド独立活性化を媒介する新しいcis要素:ホルモン調節への影響

F Saatcioglu1, T Deng, M Karin

  • 1Department of Pharmacology, School of Medicine, University of California, San Diego, La Jolla 92093-0636.

Cell
|December 17, 1993
PubMed
まとめ

新しいホルモン反応性要素 (HRE) は,甲状腺ホルモン (T3) を伴わずに強く活性化し,T3は効果を逆転させる. このユニークな要素は,c-ErbAα受容体の選択的活性化ドメイン使用を示しています.

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