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Updated: Aug 14, 2026

Formation of Covalent DNA Adducts by Enzymatically Activated Carcinogens and Drugs In Vitro and Their Determination by 32P-postlabeling
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遺伝子に基づくN-アセチルトランスフェラーゼの代謝ポリモルフィズムと,低レベルの発癌物質への環境的暴露

P Vineis1, H Bartsch, N Caporaso

  • 1Dipartimento di Scienze Biomediche e Oncologia Umana, University and Main Hospital, Torino, Italy.

Nature
|May 12, 1994
PubMed
まとめ

遺伝的変異は,身体が発癌物質を処理する方法に影響します. 遺伝子のグループであるスローアセチレータは,環境への曝露が少ない場合,より高い発がん性アダクトを示し,リスク評価に影響を与えます.

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