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Updated: Jul 31, 2026

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2つ目の信号は,腫瘍遺伝子の誘発による腫瘍発生におけるインスリン類似成長因子IIによって提供される

G Christofori1, P Naik, D Hanahan

  • 1Department of Biochemistry and Biophysics, University of California, San Francisco 94143-0534.

Nature
|June 2, 1994
PubMed
まとめ

トランス遺伝子マウスは,臓腫瘍を発症します. インスリン類似成長因子II (IGF-II) の活性化は増殖を誘発し,IGF-IIを阻害すると腫瘍の悪性腫瘍が減少し,細胞死が増加します.

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