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Updated: Aug 14, 2026

Spatio-Temporal Manipulation of Small GTPase Activity at Subcellular Level and on Timescale of Seconds in Living Cells
10:27

Spatio-Temporal Manipulation of Small GTPase Activity at Subcellular Level and on Timescale of Seconds in Living Cells

Published on: March 9, 2012

ジェム (Gem):Ras族に属する,誘導された,即時の初期のタンパク質

J Maguire1, T Santoro, P Jensen

  • 1Laboratory of Pathology, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892.

Science (New York, N.Y.)
|July 8, 1994
PubMed
まとめ

新しいグアノシン三リン酸 (GTP) 結合タンパク質であるGemがT細胞で特定されました. ゲム不調は細胞増殖を阻害し,信号伝達と細胞周期調節における役割を示唆する.

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Rab Proteins01:14

Rab Proteins

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The Ras Gene02:38

The Ras Gene

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Ras is a superfamily...
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Small GTPases - Ras and Rho

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MAPK Signaling Cascades

Mitogen-activated protein kinase, or MAPK pathway, activates three sequential kinases to regulate cellular responses such as proliferation, differentiation, survival, and apoptosis. The canonical MAPK pathway starts with a mitogen or growth factor binding to an RTK. The activated RTKs stimulate Ras, which recruits Raf or MAP3 Kinase (MAPKKK), the first kinase of the MAPK signaling cascade. Raf further phosphorylates and activates MEK or MAP2 Kinases (MAPKK), which in turn phosphorylates MAP...
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Activation and Inactivation of G Proteins

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The Ras Gene02:38

The Ras Gene

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