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TNF-αプロモーター領域の変異は,脳マラリアに対する感受性に関連しています

W McGuire1, A V Hill, C E Allsopp

  • 1Department of Paediatrics, John Radcliffe Hospital, Oxford, UK.

Nature
|October 6, 1994
PubMed
まとめ

TNF2遺伝子変異を持つ子どもは,重度の脳マラリアのリスクが7倍に増加します. この発見は,シトカイン遺伝子変異が感染症のアウトカムに与える影響を強調しています.

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