Jove
Visualize
お問い合わせ
JoVE
x logofacebook logolinkedin logoyoutube logo
JoVEについて
概要リーダーシップブログJoVEヘルプセンター
著者向け
出版プロセス編集委員会範囲と方針査読よくある質問投稿
図書館員向け
推薦の声購読アクセスリソース図書館諮問委員会よくある質問
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experimentsアーカイブ
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教員リソースセンター教員サイト
利用規約
プライバシーポリシー
ポリシー

関連する概念動画

What is the Cell Cycle?01:04

What is the Cell Cycle?

218.7K
The cell cycle refers to the sequence of events occurring throughout a typical cell’s life. In eukaryotic cells, the somatic cell cycle has two stages: interphase and the mitotic phase. During interphase, the cell grows, performs its basic metabolic functions, copies its DNA, and prepares for mitotic cell division. Then, during mitosis and cytokinesis, the cell divides its nuclear and cytoplasmic materials, respectively. This generates two daughter cells that are identical to the original...
218.7K
Cells Coordinate Growth and Proliferation02:36

Cells Coordinate Growth and Proliferation

4.7K
Cell size is a significant factor impacting cellular design, function, and fitness. There exists some internal coordination by which cells double their masses before division, thus, achieving homeostasis. Coordination between cell growth and proliferation depends on the checkpoints in between cell cycle phases. Loss of coordination or failure in the checkpoint mechanism can drive the cell to uncontrolled growth and loss of cellular function. Like dividing cells that coordinate cellular growth,...
4.7K
Mitogens and the Cell Cycle02:38

Mitogens and the Cell Cycle

7.2K
Mitogens and their receptors play a crucial role in controlling the progression of the cell cycle. However, the loss of mitogenic control over cell division leads to tumor formation. Therefore, mitogens and mitogen receptors play an important role in cancer research. For instance, the epidermal growth factor (EGF) - a type of mitogen and its transmembrane receptor (EGFR), decides the fate of the cell's proliferation. When EGF binds to EGFR, a member of the ErbB family of tyrosine kinase...
7.2K
Molecular Factors Affecting Cell Division01:27

Molecular Factors Affecting Cell Division

3.5K
Several external and internal factors influence the initiation and inhibition of cell division. For instance, the death of nearby cells or the release of human growth hormone (hGH) promotes cell division. In contrast, lack of hGH or crowding of cells can inhibit cell division.
Several proteins function as internal regulators to ensure each cell cycle stage is completed faithfully before proceeding to the next. Regulator molecules may act directly or influence the activity or production of other...
3.5K
The Cell Cycle Control System01:28

The Cell Cycle Control System

4.4K
The cell cycle regulation directs how a cell proceeds from one phase to the next and begins mitosis. The cell cycle control system includes intracellular regulatory molecules and external triggers. They provide "stop" or "advance" signals and operate at specific cell cycle stages termed checkpoints to ensure that a particular process is completed before the cell advances to the next phase.
Cyclins and cyclin-dependent kinases (Cdks) are the primary cell cycle regulators and...
4.4K
The Cell Cycle Control System02:11

The Cell Cycle Control System

12.9K
The cell cycle is an organized set of events that leads the cell to divide into two daughter cells, each containing chromosomes identical to the parent cell. It is the cell cycle that leads to the formation of an entire organism from a single-cell zygote. Besides, cell division also functions in the renewal or repair of tissues in adult multicellular eukaryotes. For example, in the bone marrow, the stem cells divide to form new blood cells. Although essential for several functions, cell...
12.9K

こちらも読む

関連記事

共著者、ジャーナル、引用グラフによってこの研究に関連する記事。

並び替え
Same author

Final analysis of the ALTTO trial: adjuvant trastuzumab in sequence or in combination with lapatinib in patients with HER2-positive early breast cancer [BIG 2-06/NCCTG N063D (Alliance)].

ESMO open·2024
Same author

Patterns of African and Asian admixture in the Afrikaner population of South Africa.

BMC biology·2020
Same author

Surgical repair <i>versus</i> conservative treatment and subacromial decompression for the treatment of rotator cuff tears: a meta-analysis of randomized trials.

The bone & joint journal·2019
Same author

Cucurbit yellow stunting disorder virus (Genus Crinivirus) Associated with the Yellowing Disease of Cucurbit Crops in Portugal.

Plant disease·2019
Same author

Silk flow-diverter stent for the treatment of complex intracranial aneurysms: A one-year follow-up multicenter study.

Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences·2018
Same author

Pulmonary hypertension: Real-world data from a Portuguese expert referral centre.

Pulmonology·2018

関連する実験動画

Updated: Oct 28, 2025

Kinematic Analysis of Cell Division and Expansion: Quantifying the Cellular Basis of Growth and Sampling Developmental Zones in Zea mays Leaves
08:31

Kinematic Analysis of Cell Division and Expansion: Quantifying the Cellular Basis of Growth and Sampling Developmental Zones in Zea mays Leaves

Published on: December 2, 2016

11.1K

細胞の長さ,細胞の成長,細胞分裂

W D Donachie, K J Begg, M Vicente

    Nature
    |November 25, 1976
    PubMed
    まとめ
    この要約は機械生成です。

    Escherichia coli (E. coli) の細菌細胞は,分裂する前に長さが2倍になります. この重要な細胞長さは,DNA複製の完成とは無関係に,より速い成長と分裂を誘発する.

    さらに関連する動画

    Comparison of Three Different Methods for Determining Cell Proliferation in Breast Cancer Cell Lines
    12:35

    Comparison of Three Different Methods for Determining Cell Proliferation in Breast Cancer Cell Lines

    Published on: September 3, 2016

    19.7K
    Measuring Cell Cycle Progression Kinetics with Metabolic Labeling and Flow Cytometry
    11:23

    Measuring Cell Cycle Progression Kinetics with Metabolic Labeling and Flow Cytometry

    Published on: May 22, 2012

    21.2K

    関連する実験動画

    Last Updated: Oct 28, 2025

    Kinematic Analysis of Cell Division and Expansion: Quantifying the Cellular Basis of Growth and Sampling Developmental Zones in Zea mays Leaves
    08:31

    Kinematic Analysis of Cell Division and Expansion: Quantifying the Cellular Basis of Growth and Sampling Developmental Zones in Zea mays Leaves

    Published on: December 2, 2016

    11.1K
    Comparison of Three Different Methods for Determining Cell Proliferation in Breast Cancer Cell Lines
    12:35

    Comparison of Three Different Methods for Determining Cell Proliferation in Breast Cancer Cell Lines

    Published on: September 3, 2016

    19.7K
    Measuring Cell Cycle Progression Kinetics with Metabolic Labeling and Flow Cytometry
    11:23

    Measuring Cell Cycle Progression Kinetics with Metabolic Labeling and Flow Cytometry

    Published on: May 22, 2012

    21.2K

    科学分野:

    • 微生物学 微生物学とは
    • 細胞生物学 細胞生物学
    • バクテリアの生理学

    背景:

    • 細菌の細胞分裂を理解することは,微生物の成長を制御するために非常に重要です.
    • Escherichia coliは,基本的な細胞生物学プロセスを研究するためのモデル生物として機能します.
    • 細胞サイズ調節は,細菌の増殖と生存力に影響を与えます.

    研究 の 目的:

    • E. coliの分裂を誘発する重要な細胞長さを調査する.
    • 細胞の伸び率,細胞分裂,DNA複製の関係を見極めるために.
    • 細胞分裂プロセスを開始するシグナルメカニズムを特定する.

    主な方法:

    • 細胞の伸びと分裂を監視するための顕微鏡技術.
    • 成長条件の分析により,重要な長さの一貫性を評価する.
    • 細胞長とDNA複製状態の相関分析.

    主要な成果:

    • E. coliの細胞は,様々な成長条件下で,最小の長さの約2倍という重要な長さに達します.
    • この重要な長さでは,細胞は急激に伸び率を上げます.
    • 細胞分裂は,臨界の長さに達してから約20分後に起こります.
    • 染色体複製は,臨界細胞長さの周りに終了しますが,分裂信号を始動しません.

    結論:

    • 細胞の長さは,DNA複製の状態ではなく,E. coliの急速な延長と分裂への移行の主要なトリガーです.
    • 臨界サイズのチェックポイントは,細菌の細胞サイクル進行を制御する.
    • この長さに依存するメカニズムは,異なる環境で分裂する前に適切な細胞サイズを確保します.