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Updated: Aug 10, 2026

Measuring Nucleotide Binding to Intact, Functional Membrane Proteins in Real Time
08:33

Measuring Nucleotide Binding to Intact, Functional Membrane Proteins in Real Time

Published on: March 11, 2021

サイクリックヌクレオチドゲートチャネル活性化の分子メカニズム

E H Goulding1, G R Tibbs, S A Siegelbaum

  • 1Department of Physiology, Howard Hughes Medical Institute, Columbia University, New York, New York 10032.

Nature
|November 24, 1994
PubMed
まとめ

サイクリックヌクレオチドゲートチャネルは,アロステリック変化によって開きます. 特定のドメインがリガンド結合とゲーティングを制御し,サイクルヌクレオチドが活性化のためのオープンチャネル状態を安定させる.

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