オーストラリアの幼い子供における日光曝露とメラノサイト性ナエヴィ
S L Harrison1, R MacLennan, R Speare
1Anton Breinl Centre, Department of Public Health and Tropical Medicine, James Cook University of North Queensland, Townsville, Australia.
Lancet (London, England)
|December 3, 1994
まとめ
幼児期に太陽に晒されると,クイーンズランド州の子どもたちのメラノサイトナエビ (モール数) が著しく増加します. 急性および慢性的な日光曝露は,メラノーマの主要なリスク要因であるモールの増加と関連しています.
科学分野:
- 皮膚科 皮膚科について
- 小児科は小児科です.
- エピデミオロジー エピデミオロジー
背景:
- オーストラリアのクイーンズランド州は,メラノーマの発生率が世界最高である.
- クイーンズランド州の子どもたちは,メラノサイトナエビ (メラノーマの主要な危険因子) の数が最も多い.
- 成人メラノーマリスクに対する日光曝露の早期の影響を遡及的に研究することは,非常に難しい課題です.
研究 の 目的:
- 幼い子供における日光曝露とメラノサイト性ナエビの発達との関連を調査する.
- ノース・クイーンズランド州の子どもたちのNAEVI数値の増加に関連した特定の日光曝露パターンを特定する.
主な方法:
- 北クイーンズランド州タウンズビルの1~6歳の506人の子どもを対象に調査を行った.
- アンケートによる日光曝露の評価.
- 標準化された国際プロトコルを使用して,量化されたメラノサイトナエビ.
主要な成果:
- 高いメラノサイトナエヴィ数 (上四半期) は,日当たり4時間以上の日焼け (aRR 3.29) と日焼け歴 (aRR 1.89) と有意に関連していました.
- メラノサイトナエウスの数は,年齢とともに増加し,皮膚の反射性が軽くなり,斑点が生じます.
- 急性および慢性的な日光曝露の両方が,子供におけるネーヴィの発達と相関しています.
結論:
- タウンズビルの強烈な紫外線曝露は,子供に早期に多くのメラノサイト性ナエヴィを引き起こします.
- 幼少期の日光曝露は,メラノサイトナエビの発達に重要な要因であり,早期の日光保護措置の必要性を強調しています.
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