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Updated: Aug 14, 2026

Visualizing Antigen Specific CD4+ T Cells using MHC Class II Tetramers
15:42

Visualizing Antigen Specific CD4+ T Cells using MHC Class II Tetramers

Published on: March 6, 2009

MHCIIクラスコンパートメントにおける抗原プレゼンテーションの調節体であるHLA-DMの蓄積

F Sanderson1, M J Kleijmeer, A Kelly

  • 1Human Immunogenetics Laboratory, Imperial Cancer Research Fund, Holborn, London, UK.

Science (New York, N.Y.)
|December 2, 1994
PubMed
まとめ

ヒト白血球抗原 (HLA) -DM分子は,HLAII級分子の適切なペプチド結合に不可欠である. HLA-DMがなければ,他のクラスIIの分子は不安定になり,不変鎖ペプチドと結合し,免疫応答に影響を与えます.

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