まとめ
細胞毒性化学療法薬のコストは,1972年から1976年の間に,安定した癌発生率にもかかわらず,大幅に増加しました. これらの高価ながん治療は,伝統的な治療法に対する安価な代替手段ではありません.
科学分野:
- 腫瘍学 腫瘍学
- 健康経済学 医療経済学
- 薬学経済学 薬学経済学
背景:
- 1972年から1976年の間に,がんの発生率と患者数は英国で安定したままでした.
- 大規模な病院の薬剤予算のうち,細胞毒薬に割り当てられた割合は,この期間に大幅に増加した.
研究 の 目的:
- 癌治療における細胞毒薬使用に関連するコストの増加を分析する.
- 手術と放射線治療と比較して,細胞毒性化学療法による経済的有効性を評価する.
主な方法:
- 病院の薬物予算と薬物使用データに関する遡及的分析.
- 薬のコスト,患者発生率,治療方法の比較.
主要な成果:
- 細胞毒薬の使用は,病院薬予算の5.1%から14%に増加した.
- 費用の上昇は,4つの特定の高価な薬の使用量と単位価格の増加によって引き起こされた.
- 費用が高騰しているにも関わらず,細胞毒性化学療法が手術や放射線治療のコスト削減の代替手段にはならない.
結論:
- 高価な細胞毒薬の使用は,治療の試みや臨床試験に限定されるべきである.
- 進行がんの緩和ケアのために,より安価な細胞毒性薬の使用を最適化するために,さらなる研究が必要です.
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