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Updated: Jul 27, 2026

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転写因子c-Junを調節するストレス活性化経路におけるSAPK/ERKキナーゼ-1の役割

I Sánchez1, R T Hughes, B J Mayer

  • 1Diabetes Research Laboratory, Massachusetts General Hospital East, Charlestown.

Nature
|December 22, 1994
PubMed
まとめ

ストレス活性化タンパク質キナーゼ (SAPK) は,細胞のストレス反応に不可欠です. この研究は,SAPK/ERK キナーゼ-1 (SEK1) を新しい上流活性化剤として特定し,ストレスから遺伝子活性化までの重要なシグナル伝達経路を定義しています.

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