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Updated: Jul 6, 2026

Atomic Force Microscopy Investigations of DNA Lesion Recognition in Nucleotide Excision Repair
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Published on: May 24, 2017

Vmw65 (VP16) による差分認識の基礎として,Oct-1 POUドメイン-DNA複合体のサイト固有の構成変化

S Walker1, S Hayes, P O'Hare

  • 1Marie Curie Research Institute, Oxted, Surrey, England.

Cell
|December 2, 1994
PubMed
まとめ

POUドメインの横に並ぶ規制要素は,特定のDNAに結合した適合性を誘導することによって,Vmw65 (VP16) の相互作用を決定する. 変異により,この形状の変化は,POU結合だけでなく,Vmw65認識に不可欠であることが明らかになりました.

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