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Updated: Jun 19, 2026

Preparation of Oligomeric β-amyloid1-42 and Induction of Synaptic Plasticity Impairment on Hippocampal Slices
04:41

Preparation of Oligomeric β-amyloid1-42 and Induction of Synaptic Plasticity Impairment on Hippocampal Slices

Published on: July 15, 2010

ペロキシド水素は,アミロイドベータタンパク質の毒性を媒介する

C Behl1, J B Davis, R Lesley

  • 1Salk Institute for Biological Studies, San Diego, California 92186-5800.

Cell
|June 17, 1994
PubMed
まとめ

アミロイドベータタンパク質は,アルツハイマー病に関連したプロセスであるフリーラジカルの損傷によってニューロン死亡を引き起こす. 抗酸化物質とカタラゼは,この毒性から保護し,酸化ストレスが重要な役割を果たしていることを示しています.

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A11-positive β-amyloid Oligomer Preparation and Assessment Using Dot Blotting Analysis06:17

A11-positive β-amyloid Oligomer Preparation and Assessment Using Dot Blotting Analysis

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Interactions with and Membrane Permeabilization of Brain Mitochondria by Amyloid Fibrils15:04

Interactions with and Membrane Permeabilization of Brain Mitochondria by Amyloid Fibrils

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