タンパク質コファクターの存在と欠如におけるRNA酵素の基質の異なる進化

F Liu1, S Altman

  • 1Department of Biology, Yale University, New Haven, Connecticut 06520.

Cell
|July 1, 1994
PubMed
まとめ

研究者はRNAase P酵素基板を見つけるために進化をシミュレートしました. タンパク質コファクタは酵素の基板範囲を拡大し,リボ核タンパク質酵素と4.5SRNAが前駆体tRNAの後に進化したことを示唆しています.

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