左心室の構造が高血圧の発生率に与える影響. フレミングハム心臓研究 (The Framingham Heart Study) が実施されている
1Framingham Heart Study, Mass 01701.
Circulation
|July 1, 1994
まとめ
ノルモテンシブな成人の左心室質量と壁の厚さの増加は,高血圧の発症と関連しています. エコーカルディオグラフィは,高血圧のリスクのある個人を特定するのに役立ちます.
科学分野:
- 心臓病学 心臓病学
- 高血圧の研究 高血圧の研究
- 診断用イメージング
背景:
- 左心室高縮症 (LVH) は高血圧の初期指標である.
- 高血圧の発症における左心室質量増加の役割は不明である.
- 心臓の構造の変化は高血圧の発生に先行する可能性があります.
研究 の 目的:
- 左心室質量と高血圧の発生率との関連を調査する.
- 高血圧の発達に対する心的特徴のエコーカルジオグラフィの影響を評価する.
- 心臓の構造が将来の高血圧を予測するかどうかを判断する.
主な方法:
- フレミングハム・ハート・アンド・オフスプリング・スタディのノルモテンシブ参加者の分析.
- ベースラインエコーカルディオグラフィは,左心室の質量と壁の厚さを測定します.
- 4年間,インシデント高血圧を特定するための縦断的なフォローアップ.
主要な成果:
- ベースラインの左心室質量 (P=.01) と壁の厚さ (P=.02) の増加は高血圧を予測した.
- 左心室質量指数の1SD増加は,高血圧の確率を20%上昇させた (OR=1.20).
- 左心室壁の厚さの1SD増加は,高血圧の確率を16% (OR=1.16) 増加させた.
結論:
- 左心室の質量と壁の厚さの上昇は,正常血圧の成人における高血圧の発達と関連しています.
- エコーカルディオグラフィーは,抗高血圧療法を必要とする個人を特定するのに役立ちます.
- 心臓の構造に基づいた早期の介入戦略は,さらなる調査が必要である.
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