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Updated: Aug 10, 2026

Characterize Disease-related Mutants of RAF Family Kinases by Using a Set of Practical and Feasible Methods
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ファスファディチルイノシトール-3-OHキナーゼは,Rasの直接標的として使用されます

P Rodriguez-Viciana1, P H Warne, R Dhand

  • 1Imperial Cancer Research Fund, London, UK.

Nature
|August 18, 1994
PubMed
まとめ

Rasタンパク質は,フォスファティディルイノシトール-3-OHキナーゼに直接結合し,その活性を調節する. この相互作用は細胞の信号伝達経路に影響を与え,細胞の成長と脂質の産生に影響を与えます.

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