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Updated: Jul 30, 2026

Measuring G-protein-coupled Receptor Signaling via Radio-labeled GTP Binding
10:13

Measuring G-protein-coupled Receptor Signaling via Radio-labeled GTP Binding

Published on: June 9, 2017

内分泌機能の増減を伴う患者でGsαからGDPの急速な放出

T Iiri1, P Herzmark, J M Nakamoto

  • 1Department of Pharmacology, University of California, San Francisco 94143-0450.

Nature
|September 8, 1994
PubMed
まとめ

新しいGsアルファサブユニット変異は,アデニリルサイクラスを構成的に活性化することによって,テストオキシキソシスと型Iaの擬似ヒポパラチロイド症の両方を引き起こします. この突然変異は,ホルモンに依存しないテストステロンの分泌と,体温でGsの活性低下につながる.

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