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Updated: Aug 10, 2026

An Ecdysone Receptor-based Singular Gene Switch for Deliberate Expression of Transgene with Robustness, Reversibility, and Negligible Leakiness
06:21

An Ecdysone Receptor-based Singular Gene Switch for Deliberate Expression of Transgene with Robustness, Reversibility, and Negligible Leakiness

Published on: May 7, 2018

HMGのようなタンパク質で,転写活性化剤を抑制剤に切り替えることができる

N Lehming1, D Thanos, J M Brickman

  • 1Department of Biochemistry and Molecular Biology, Harvard University, Cambridge, Massachusetts 02138.

Nature
|September 8, 1994
PubMed
まとめ

ドロソフィラ・DSP1タンパク質は,転写因子DorsalとNF-kappa Bを活性化因子から抑制因子に変換する. このスイッチは,HMGタンパク質を強調する負の規制要素に依存しています.

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