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Updated: Aug 15, 2026

Analysis of Spliceosomal snRNA Localization in Human Hela Cells Using Microinjection
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U1 snRNPが欠乏したプレ-mRNAスプライシング反応のSRタンパク質による補充

J D Crispino1, B J Blencowe, P A Sharp

  • 1Center for Cancer Research, Massachusetts Institute of Technology, Cambridge 02139.

Science (New York, N.Y.)
|September 23, 1994
PubMed
まとめ

高濃度のSRタンパク質は,U1小核リボヌクレオプロテイン (snRNP) がなくても,プレ-mRNAスプライシングを開始することができます. この発見は,遺伝子発現の調節を理解するために不可欠な,スプライソーム組成のための新しい経路を明らかにします.

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