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Updated: Jul 24, 2026

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ウィルムスの腫瘍に関与するインスリン類似成長因子II遺伝子インプリントの緩和

O Ogawa1, M R Eccles, J Szeto

  • 1Department of Biochemistry, University of Otago, Dunedin, New Zealand.

Nature
|April 22, 1993
PubMed
まとめ

ゲノムインプリントの欠陥,特にインスリン型の成長因子II (IGF2) 遺伝子は,ウィルムスの腫瘍発症に関連しています. バイアレル性IGF2発現につながるインプリントの緩解は,新しいがんのメカニズムを示唆しています.

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