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関連する概念動画

Carbon Skeletons01:12

Carbon Skeletons

84.6K
Life on Earth is carbon-based, as all macromolecules that make up living organisms contain carbon atoms. All organic compounds have a carbon backbone. Each carbon atom is tetravalent and can bond with four other atoms, making it an extraordinarily flexible component of biological molecules. Because carbon’s valence electrons are stable, it rarely becomes an ion. As the carbon chain increases in length, structural modifications such as ring structures, double bonds, and branching side...
84.6K
Gross Anatomy of Bone01:17

Gross Anatomy of Bone

14.3K
The two main features of a long bone are the diaphysis and the epiphysis.
The diaphysis is the tubular shaft that runs between the proximal and distal ends of the bone. The walls of the diaphysis are composed of dense and hard compact bone made of numerous osteons — the functional unit of the compact bone. The hollow region in the diaphysis is called the medullary cavity, which harbors the bone marrow. In infants and children, this marrow cavity is filled with red marrow, whereas in...
14.3K
Compact Bone01:27

Compact Bone

22.4K
Most bones contain compact and spongy osseous tissue, but their distribution and concentration vary based on the bone's overall function.
Compact bone, also called cortical bone, is the denser, stronger of the two types of bone tissue. It is found under the periosteum and in the diaphyses of long bones, where it provides support and protection. The microscopic structural unit of compact bone is called an osteon, or haversian system. Each osteon is composed of concentric rings of calcified...
22.4K
Virtual Work for a System of Connected Rigid Bodies01:06

Virtual Work for a System of Connected Rigid Bodies

858
Virtual work is a powerful method used to solve problems involving several connected rigid bodies. When the system is in equilibrium, virtual work is zero. This allows the calculation of the resulting forces when a system undergoes a virtual displacement. When attempting to analyze such a system, first, use a free-body diagram, where an independent coordinate represents the configuration of the links, and mark its deflected position resulting from the positive virtual displacement.
Next,...
858
Spinal Cord: Cross-sectional Anatomy01:16

Spinal Cord: Cross-sectional Anatomy

5.7K
The cross-sectional anatomy of the spinal cord offers a detailed view of its complex structure and function within the central nervous system. At the core of the spinal cord lies the gray matter, characterized by its butterfly or "H"-shaped appearance in cross-section. This central region is enveloped by white matter, with the overall structure divided into symmetrical halves by the dorsal median sulcus and the ventral median fissure.
Gray Matter and its Components
Central to the gray matter is...
5.7K
Steel Manufacturing01:26

Steel Manufacturing

1.5K
Steel manufacturing is a multi-stage process that begins by smelting iron ore into cast iron in a blast furnace. This initial stage involves layering iron ore with coke, a type of fuel, and crushed limestone within the furnace. The coke is ignited with a high volume of air, leading to the creation of carbon monoxide, which acts to reduce the iron ore to pure iron.
During this smelting process, limestone plays a crucial role by forming slag. Slag captures impurities within the molten iron, such...
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関連する実験動画

Updated: May 4, 2026

Operation of the Collaborative Composite Manufacturing CCM System
10:09

Operation of the Collaborative Composite Manufacturing CCM System

Published on: October 1, 2019

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核骨格に付着した複製工場の視覚化.

P Hozák1, A B Hassan, D A Jackson

  • 1Sir William Dunn School of Pathology, University of Oxford, England.

Cell
|April 23, 1993
PubMed
まとめ

DNA複製は,細胞骨格に付着した離散的な場所,または"工場"で起こります. 新しく合成されたDNAは,周囲のクロマチンに広がる前に,これらの工場で最初に現れる.

科学分野:

  • 細胞生物学 細胞生物学
  • 分子生物学は分子生物学である.
  • 遺伝学 遺伝学とは

背景:

  • DNA複製は細胞分裂に不可欠である.
  • DNA複製部位の空間的組織は完全に理解されていません.

研究 の 目的:

  • 核内のDNA合成の物理的な場所の視覚化と特徴付け.
  • これらの場所でのDNA複製のダイナミクスを調査する.

主な方法:

  • HeLa細胞はアガロースマイクロビーズにカプセル化されました.
  • DNA合成部位は,バイオチン-11-dUTPと免疫ラベルを貼った.
  • 光と電子顕微鏡を用いて核構造を調べました.
  • 基礎構造を視覚化するためにクロマチンは部分的に除去されました.

主要な成果:

  • 核ごとに約150のDNA合成の焦点部位が観察されました.
  • これらのサイトにはDNAポリメラーゼαと増殖細胞核抗原が含まれていた.
  • 電子顕微鏡では,核骨格に付着した離散的な卵状の体を発見しました.
  • バイオチンの組み込みは,最初にこれらの卵状体内で発生し,それからクロマチンに広がった.

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Simulation of a Scaled Assembly Process with Collaboration of a Robotic Arm and Monitoring through a Vision System for Quality Control
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関連する実験動画

Last Updated: May 4, 2026

Operation of the Collaborative Composite Manufacturing CCM System
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Operation of the Collaborative Composite Manufacturing CCM System

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Pedicle Screw Placement Using an Augmented Reality Head-Mounted Display in a Porcine Model
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Simulation of a Scaled Assembly Process with Collaboration of a Robotic Arm and Monitoring through a Vision System for Quality Control
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Simulation of a Scaled Assembly Process with Collaboration of a Robotic Arm and Monitoring through a Vision System for Quality Control

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結論:

  • DNA複製は,核骨格に付着した固定されたポリメリゼーション工場で行われます.
  • 複製は,DNAテンプレートがこれらの静止工場を移動するにつれて進行します.