内生性オピオイドペプチドの局所鎮痛効果

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Updated: Nov 10, 2026

Assessment of Morphine-induced Hyperalgesia and Analgesic Tolerance in Mice Using Thermal and Mechanical Nociceptive Modalities
07:23

Assessment of Morphine-induced Hyperalgesia and Analgesic Tolerance in Mice Using Thermal and Mechanical Nociceptive Modalities

Published on: July 29, 2014

C Stein1, A H Hassan, K Lehrberger

  • 1Department of Anesthesiology and Critical Care Medicine, Johns Hopkins University, Baltimore, Maryland.

Lancet (London, England)
|August 7, 1993
PubMed
まとめ

膝関節液中のオピオイドペプチドは,局所受容体を活性化することによって痛みを軽減します. これらの受容体を遮断すると,手術後の痛みが増加し,新しい外周疼痛緩和戦略を示唆します.

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