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Updated: Aug 19, 2026

Measurement of In Vitro Integration Activity of HIV-1 Preintegration Complexes
10:34

Measurement of In Vitro Integration Activity of HIV-1 Preintegration Complexes

Published on: February 22, 2017

HIV-1マトリックスタンパク質内の核局所化信号で,分裂しない細胞の感染を制御する

M I Bukrinsky1, S Haggerty, M P Dempsey

  • 1Department of Pathology and Microbiology, University of Nebraska Medical Center, Omaha 68198-5120.

Nature
|October 14, 1993
PubMed
まとめ

ヒト免疫不全ウイルス1型 (HIV-1) のガグマトリックスタンパク質は,核の局所化配列を含み,分裂しない細胞でウイルスの複製を可能にします. この配列の変異により,HIV-1はオンコレトロウイルスのように振る舞い,複製のために細胞分裂を必要とする.

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