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Assessment of Vascular Function in Patients With Chronic Kidney Disease
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足首/腕の血圧指数が低い高血圧の成人の罹患率と死亡率
A B Newman1, K Sutton-Tyrrell, M T Vogt
1Department of Medicine, Medical College of Pennsylvania, Pittsburgh 15212.
JAMA
|July 28, 1993
まとめ
足首/腕の低血圧指数 (AAI) は,シストリック高血圧の高齢者の心血管リスクの増加の有意な予測指標です. この発見は,AAIを心血管疾患および死亡率の重要なマーカーとして強調しています.
科学分野:
- 心血管医学 心血管医学
- ゲリアトリクス ゲリアトリクス
- 血管の健康 血管の健康とは
背景:
- 周辺動脈疾患 (PAD) は,心血管疾患の重要な危険因子です.
- 足首と腕の血圧指数 (AAI) は,PADを評価するために使用される非侵襲的測定法です.
- 高齢者のシストリック高血圧は,心血管疾患のリスクの増加に関連する一般的な状態です.
研究 の 目的:
- 足首/腕の低血圧指数 (AAI) と短期的な心血管疾患および死亡率との関連を調べる.
- AAIがシストリック高血圧の高齢者における有害な心血管疾患の予測因子であるかどうかを判断する.
主な方法:
- 1~2年間のフォローアップ期間を持つ前向きなコホート研究.
- 収縮性高血圧と診断された1537人の高齢男女を対象に調査した.
- 足首/腕の血圧指数 (AAI) の測定および全因死亡率,冠動脈疾患 (CHD) 死亡率,心血管疾患 (CVD) 罹病率および死亡率の評価.
主要な成果:
- 低AAI (≤0.9) は,参加者の25.5%で観察され,主要な心血管リスク要因と関連していました.
- 低AAIを有する個人は,全死亡率 (3.8),CHD死亡率 (3.24),およびCVD死亡率 (3.7) の年齢および性別調整された相対リスクが著しく高かった.
- ベースラインのCVDおよびリスク要因を調整した後,低AAIは,総死亡率 (4.1) およびCVDの罹病率/死亡率 (2.4) の有意な予測因子であり続けました.
結論:
- 足首/腕の低血圧指数 (AAI) は,シストリック高血圧の高齢者の罹患率と死亡率の有意な独立した予測指標です.
- AAIは,高血圧の高齢者集団におけるリスクの階層化のための貴重なツールとして機能します.
- 低AAIの早期発見は,心血管疾患の発生を減らすための適切な介入を促進する可能性があります.
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